Beyond the Whole-Genome Duplication: Phylogenetic Evidence for an Ancient Interspecies Hybridization in the Baker's Yeast Lineage

作者: Marina Marcet-Houben , Toni Gabaldón

DOI: 10.1371/JOURNAL.PBIO.1002220

关键词: PaleogeneticsPhylogenomicsLineage (evolution)GeneticsPhylogeneticsGenomeBiologyProteomeGene duplicationPhylogenetic treeGeneral NeuroscienceGeneral Agricultural and Biological SciencesGeneral Biochemistry, Genetics and Molecular BiologyGeneral Immunology and Microbiology

摘要: Whole-genome duplications have shaped the genomes of several vertebrate, plant, and fungal lineages. Earlier studies focused on establishing when these events occurred elucidating their functional evolutionary consequences, but we still lack sufficient understanding how genome first originated. We used phylogenomics to study ancient duplication in yeast Saccharomyces cerevisiae lineage found compelling evidence for existence a contemporaneous interspecies hybridization. propose that doubling was direct consequence this hybridization it served provide stability recently formed allopolyploid. This scenario provides mechanism origin originated from brings new perspective interpretation consequences whole-genome duplications.

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