作者: Marina Marcet-Houben , Toni Gabaldón
DOI: 10.1371/JOURNAL.PBIO.1002220
关键词: Paleogenetics 、 Phylogenomics 、 Lineage (evolution) 、 Genetics 、 Phylogenetics 、 Genome 、 Biology 、 Proteome 、 Gene duplication 、 Phylogenetic tree 、 General Neuroscience 、 General Agricultural and Biological Sciences 、 General Biochemistry, Genetics and Molecular Biology 、 General Immunology and Microbiology
摘要: Whole-genome duplications have shaped the genomes of several vertebrate, plant, and fungal lineages. Earlier studies focused on establishing when these events occurred elucidating their functional evolutionary consequences, but we still lack sufficient understanding how genome first originated. We used phylogenomics to study ancient duplication in yeast Saccharomyces cerevisiae lineage found compelling evidence for existence a contemporaneous interspecies hybridization. propose that doubling was direct consequence this hybridization it served provide stability recently formed allopolyploid. This scenario provides mechanism origin originated from brings new perspective interpretation consequences whole-genome duplications.