Neuroticism and conscientiousness respectively constrain and facilitate short-term plasticity within the working memory neural network.

摘要: Individual differences in cognitive efficiency, particularly relation to working memory (WM), have been associated both with personality dimensions that reflect enduring regularities brain configuration, and short-term neural plasticity, reflects task-related changes connectivity. To elucidate the relationship of these two divergent mechanisms, we tested hypothesis dimensions, which aspects inform about neurobiological framework within short-term, as measured by effective connectivity, can be facilitated or constrained. As WM consistently engages dorsolateral prefrontal (DLPFC), parietal (PAR), anterior cingulate cortex (ACC), specified a network model bidirectional, ipsilateral, contralateral connections between regions from functional magnetic resonance imaging dataset obtained 40 healthy adults while performing 3-back task. Task-related connectivity this were estimated using Dynamic Causal Modelling. Personality was evaluated along major Neuroticism, Extraversion, Openness Experience, Agreeableness, Conscientiousness. Only relevant task-dependent Neuroticism Conscientiousness respectively constrained neuroplastic responses network. These results suggest individual efficiency arise interplay plasticity configuration.