Ethical and Scientific Pitfalls Concerning Laboratory Research with Non-Human Primates, and Possible Solutions.

作者: Constança Carvalho , Augusta Gaspar , Andrew Knight , Luís Vicente

DOI: 10.3390/ANI9010012

关键词: HarmAnimal Use AlternativesLegislationEngineering ethicsDeontological ethicsUtilitarianismEthics committeePsychologyNon-humanLaboratory research

摘要: Basic and applied laboratory research, whenever intrusive or invasive, presents substantial ethical challenges for committees, be it with human beings non-human animals. In this paper we discuss the use of primates (NHPs), mostly as animal models, in based research. We examine two frameworks that support current legislation guidelines: deontology utilitarianism. While research is regulated under deontological principles, guidelines rely on argue utilitarian framework inadequate purpose: one hand, almost impossible to accurately predict benefits a study all potential stakeholders; other harm inflicted NHPs (and animals) used extensive despite increasing efforts ethics committees community address this. Although utilitarianism are both valid frameworks, advocate approach more suitable, since arguably have moral duties NHPs. provide suggestions how ensure currently conducted settings shifts towards approaches abide by principles. assert would not impede reasonable scientific

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