HISTAMINE IN THE HEART AND SPINAL CORD OF HYPERTENSIVE RATS

作者: J.P. Chalmers , P.R.C. Howe , J.C. Provis , M.J. West

DOI: 10.1016/B978-1-4832-8363-0.50356-6

关键词: Internal medicineSympathectomyEndocrinologySpinal cordHistamineAnesthesiaMedicine

摘要: Concentrations of histamine (HA) in hearts and spinal cords normotensive (WKY), spontaneously hypertensive (SHR) stroke-prone rats (SPR) were measured by radioenzymatic assay. There no significant differences between strains cord HA. However, cardiac HA both SHR SPR was more than double the WKY value before onset hypertension, remained elevated chronically rats. a corresponding increase mast cells sections taken from young SPR. The elevation unaffected prior sympathectomy with 6-hydroxydopamine HC1 (6-ODHA).

参考文章(8)
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
Terry L. Holcslaw, Max D. Adams, Tom S. Miya, William F. Bousquet, Histamine disposition in the hypertensive rat Life Sciences. ,vol. 14, pp. 769- 784 ,(1974) , 10.1016/0024-3205(74)90460-3
L. Finch, P. E. Hicks, The cardiovascular effects of intraventricularly administered histamine in the anaesthetised rat. Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 293, pp. 151- 157 ,(1976) , 10.1007/BF00499220
Jean-Charles Schwartz, Histamine as a transmitter in brain Life Sciences. ,vol. 17, pp. 503- 517 ,(1975) , 10.1016/0024-3205(75)90083-1
David P. Henry, Barbra J. Starman, David G. Johnson, Robert H. Williams, A sensitive radioenzymatic assay for norepinephrine in tissues and plasma Life Sciences. ,vol. 16, pp. 375- 384 ,(1975) , 10.1016/0024-3205(75)90258-1
U. TRENDELENBURG, Stimulation of Sympathetic Centers by Histamine Circulation Research. ,vol. 5, pp. 105- 110 ,(1957) , 10.1161/01.RES.5.1.105
K Okamoto, Establishment of the strokeprone spontaneously hypertensive rat (SHR) Circulation Research. ,vol. 1, pp. 143- 153 ,(1972)