Sleep related respiratory disorders in end-stage renal disease patients on peritoneal dialysis.

摘要: STUDY OBJECTIVE To assess the possible effects of peritoneal dialysis (PD) on sleep-related respiration, which might result from dialysate bulk load in abdomen and/or alterations metabolic control respiration during sleep. DESIGN Subjective and objective measures sleep were prospectively compared randomly assigned nights with PD fluid (2.0 L) without cavity 11 end-stage renal disease (ESRD) patients PD. SETTING Tertiary-referral university hospital. PATIENTS AND METHODS Fifteen consecutive who complained chronic disturbance requested sedative selected. Four declined polysomnographic studies. Consequently, ESRD (8 males 3 females) a mean age 63 +/- 4 (SEM) years studied. RESULTS Eight reported multiple types difficulties. Polysomnographic recordings revealed significant primarily obstructive apnea 6 at least 1 2 nights. Arterial blood pH, paO2, paCO2 did not differ between group as whole. In apnea, PaO2 was significantly lower (p less than 0.05) night (PaO2 = 78 7 mmHg) 92 mmHg). apneic patients, amount drained morning negatively correlated minimum arterial oxygen saturation (r -0.94; p 0.005). CONCLUSIONS This study indicates relationship syndrome. These data suggest that may be susceptible to complications effect desaturation.