作者: Xuan Zhao , Nabil El-Tayar , Michael D. Bentley
DOI:
关键词: Stereochemistry 、 Combinatorial chemistry 、 PEG ratio 、 Linker 、 Serine 、 Moiety 、 Conjugate 、 Residue (chemistry) 、 Amino acid 、 Bifunctional 、 Chemistry
摘要: PEG-LHRH analog conjugates, where a PEG moiety is covalently bound to serine residue of LHRH either directly or via bifunctional linker molecule, such as an amino acid, and methods for producing these conjugates are provided in the present invention. Also pharmaceutical composition method treating pathologies which administration beneficial.