Protein adsorption on magnesium and its alloys: A review

作者: Sarah Höhn , Sannakaisa Virtanen , Aldo R. Boccaccini

DOI: 10.1016/J.APSUSC.2018.08.173

关键词: Protein adsorptionPolarization (electrochemistry)MetalAdsorptionMagnesiumChemical engineeringX-ray photoelectron spectroscopyDielectric spectroscopyCorrosionMaterials science

摘要: Abstract The initial interaction of biomaterials with the biological environment is based on adsorption proteins surface and ions water molecules to form various reactive interfaces. Understanding protein mechanisms, kinetics, thermodynamics essential improve design new biocompatible materials control solid surfaces. Magnesium its alloys are promising for biodegradable metallic devices due several advantages, including reduced stress shielding effect in case orthopedic implants, removing requirement a second surgery implant removal. Appropriate magnesium Mg applications bone tissue regeneration effective integration implants. In this review, we summarize discuss previous studies magnesium-protein interactions, surfaces as well influence corrosion. most cases, corrosion was determined using polarization curves, electrochemical impedance spectroscopy (EIS), X-ray photoelectron (XPS). results show inhibited degradation insoluble salt formation (barrier layer) or unstable porous layers followed by higher rates depending substrate (cpMg alloys) and/or media. A comparison use different solutions reactions (with without proteins) presented layer discussed. media mechanism highlighted, which significantly affects in-vivo in-vitro behavior, being thus high relevance application medicine.

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