Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
作者： Yuliya Pylayeva-Gupta , Kyoung Eun Lee , Cristina H. Hajdu , George Miller , Dafna Bar-Sagi
DOI: 10.1016/J.CCR.2012.04.024
关键词: Downregulation and upregulation 、 CD8 、 KRAS 、 Stromal cell 、 Adenocarcinoma 、 HEK 293 cells 、 Granulocyte macrophage colony-stimulating factor 、 Immunohistochemistry 、 Cancer research 、 Biology
摘要: … Mice were depleted of CD8 + T cells via intraperitoneal injection of control rat IgG antibody (… The efficiency of CD8 + T cell depletion was assessed by FACS of splenic tissues using anti-…
core.ac.uk
sci-hub.se 参考文章(50)
Cristina Agbunag, Kyoung Eun Lee, Serena Buontempo, Dafna Bar‐Sagi, Pancreatic Duct Epithelial Cell Isolation and Cultivation in Two-Dimensional and Three-Dimensional Culture Systems Methods in Enzymology. ,vol. 407, pp. 703- 710 ,(2006) , 10.1016/S0076-6879(05)07055-2
P N Cockerill, M A Vadas, C S Osborne, Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus Journal of Immunology. ,vol. 155, pp. 226- 235 ,(1995)
Boris Linard, Stéphane Bézieau, Houssem Benlalam, Nathalie Labarrière, Yannick Guilloux, Elisabeth Diez, Francine Jotereau, A ras-Mutated Peptide Targeted by CTL Infiltrating a Human Melanoma Lesion Journal of Immunology. ,vol. 168, pp. 4802- 4808 ,(2002) , 10.4049/JIMMUNOL.168.9.4802
Vincenzo Bronte, Anna Cabrelle, Nicholas P. Restifo, Dale B. Chappell, Elisa Apolloni, Patrick Hwu, Michael Wang, Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. Journal of Immunology. ,vol. 162, pp. 5728- 5737 ,(1999)
Sergio A. Quezada, Karl S. Peggs, Tyler R. Simpson, James P. Allison, Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication Immunological Reviews. ,vol. 241, pp. 104- 118 ,(2011) , 10.1111/J.1600-065X.2011.01007.X
Ralph H. Hruban, Jason Y. Park, Seung Mo Hong, Michael Goggins, Molecular Signatures of Pancreatic Cancer Archives of Pathology & Laboratory Medicine. ,vol. 135, pp. 716- 727 ,(2011) , 10.1043/2010-0566-RA.1
Shari Pilon-Thomas, Nadine Nelson, Nasreen Vohra, Maya Jerald, Laura Pendleton, Karoly Szekeres, Tomar Ghansah, Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function. PLOS ONE. ,vol. 6, ,(2011) , 10.1371/JOURNAL.PONE.0027729
Yuliya Pylayeva-Gupta, Elda Grabocka, Dafna Bar-Sagi, RAS oncogenes: weaving a tumorigenic web Nature Reviews Cancer. ,vol. 11, pp. 761- 774 ,(2011) , 10.1038/NRC3106
Michel DuPage, Ann F. Cheung, Claire Mazumdar, Monte M. Winslow, Roderick Bronson, Leah M. Schmidt, Denise Crowley, Jianzhu Chen, Tyler Jacks, Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression Cancer Cell. ,vol. 19, pp. 72- 85 ,(2011) , 10.1016/J.CCR.2010.11.011
Barbara Mroczko, Maciej Szmitkowski, Urszula Wereszczyńska-Siemiątkowska, Grażyna Jurkowska, Hematopoietic cytokines in the sera of patients with pancreatic cancer. Clinical Chemistry and Laboratory Medicine. ,vol. 43, pp. 146- 150 ,(2005) , 10.1515/CCLM.2005.024