Structure-Activity Correlations for the Ferric Uptake Regulation (FUR) Repressor Protein of Escherichia Coli K12

作者: Stephen del Cardayre , J. B. Neilands

DOI: 10.1007/978-1-4615-3810-3_28

关键词: FerricIron absorptionChemical modificationChemistryRepressorMetabolismA proteinThiolEscherichia coliBiochemistry

摘要: The purpose of this chapter will be to give an overview certain features microbial iron metabolism and record what is known at the moment writing regarding molecular mechanism regulation high affinity absorption in Escherichia coli K-12. Evidence obtained by chemical modification experiments suggests that thiol groups may play a role activity protein (Fur) regulating bacterial species.

参考文章(34)
Peter C. Jocelyn, Spectrophotometric assay of thiols Methods in Enzymology. ,vol. 143, pp. 44- 67 ,(1987) , 10.1016/0076-6879(87)43013-9
Metal--DNA chemistry American Chemical Society. ,(1989) , 10.1021/BK-1989-0402
W. Flitter, D.A. Rowley, B. Halliwell, Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts FEBS Letters. ,vol. 158, pp. 310- 312 ,(1983) , 10.1016/0014-5793(83)80602-4
Victor De Lorenzo, Fabio Giovannini, Marta Herrero, J.B. Neilands, Metal ion regulation of gene expression. Fur repressor-operator interaction at the promoter region of the aerobactin system of pColV-K30. Journal of Molecular Biology. ,vol. 203, pp. 875- 884 ,(1988) , 10.1016/0022-2836(88)90113-1
J A Stoebner, S M Payne, Iron-regulated hemolysin production and utilization of heme and hemoglobin by Vibrio cholerae. Infection and Immunity. ,vol. 56, pp. 2891- 2895 ,(1988) , 10.1128/IAI.56.11.2891-2895.1988
A Bagg, J B Neilands, Molecular mechanism of regulation of siderophore-mediated iron assimilation. Microbiological Research. ,vol. 51, pp. 509- 518 ,(1987) , 10.1128/MR.51.4.509-518.1987
P J Warner, P H Williams, A Bindereif, J B Neilands, ColV plasmid-specific aerobactin synthesis by invasive strains of Escherichia coli. Infection and Immunity. ,vol. 33, pp. 540- 545 ,(1981) , 10.1128/IAI.33.2.540-545.1981
K Poole, V Braun, Iron regulation of Serratia marcescens hemolysin gene expression. Infection and Immunity. ,vol. 56, pp. 2967- 2971 ,(1988) , 10.1128/IAI.56.11.2967-2971.1988