Themis, a T cell-specific protein important for late thymocyte development.
作者： Renaud Lesourne , Shoji Uehara , Jan Lee , Ki-Duk Song , LiQi Li
DOI: 10.1038/NI.1768
关键词: CD8 、 T-cell receptor 、 Signal transduction 、 Molecular biology 、 T cell 、 Biology 、 Embryonic stem cell 、 Thymocyte 、 Cellular differentiation 、 Receptor
摘要: During positive selection, thymocytes transition through a stage during which T cell antigen receptor (TCR) signaling controls CD4-versus-CD8 lineage 'choice' and subsequent …
nature.com
sci-hub.se 参考文章(40)
Ross Anderson, Serge Vaudenay, Minding your p's and q`s international cryptology conference. ,vol. 1163, pp. 26- 35 ,(1996) , 10.1007/BFB0034832
DJ Veis, Ch L Sentman, EA Bach, SJ Korsmeyer, None, Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. Journal of Immunology. ,vol. 151, pp. 2546- 2554 ,(1993)
Ricardo Cibotti, Jennifer A Punt, Krishna S Dash, Susan O Sharrow, Alfred Singer, Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals Immunity. ,vol. 6, pp. 245- 255 ,(1997) , 10.1016/S1074-7613(00)80327-1
Guo Fu, Sébastien Vallée, Vasily Rybakin, Marielena V McGuire, Jeanette Ampudia, Claudia Brockmeyer, Mogjiborahman Salek, Paul R Fallen, John A H Hoerter, Anil Munshi, Yina H Huang, Jianfang Hu, Howard S Fox, Karsten Sauer, Oreste Acuto, Nicholas R J Gascoigne, Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling Nature Immunology. ,vol. 10, pp. 848- 856 ,(2009) , 10.1038/NI.1766
Rémy Bosselut, CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals Nature Reviews Immunology. ,vol. 4, pp. 529- 540 ,(2004) , 10.1038/NRI1392
Jung-Hyun Park, Stanley Adoro, Philip J Lucas, Sophia D Sarafova, Amala S Alag, Loretta L Doan, Batu Erman, Xiaolong Liu, Wilfried Ellmeier, Remy Bosselut, Lionel Feigenbaum, Alfred Singer, 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR Nature Immunology. ,vol. 8, pp. 1049- 1059 ,(2007) , 10.1038/NI1512
Weiguo Zhang, Connie L Sommers, Deborah N Burshtyn, Christopher C Stebbins, Jan B DeJarnette, Ronald P Trible, Alexander Grinberg, Henry C Tsay, Helena M Jacobs, Craig M Kessler, Eric O Long, Paul E Love, Lawrence E Samelson, Essential Role of LAT in T Cell Development Immunity. ,vol. 10, pp. 323- 332 ,(1999) , 10.1016/S1074-7613(00)80032-1
Parinaz Aliahmad, Jonathan Kaye, Commitment issues: linking positive selection signals and lineage diversification in the thymus Immunological Reviews. ,vol. 209, pp. 253- 273 ,(2006) , 10.1111/J.0105-2896.2006.00345.X
Gabriela Hernández-Hoyos, Michele K. Anderson, Chi Wang, Ellen V. Rothenberg, Jose Alberola-Ila, GATA-3 Expression Is Controlled by TCR Signals and Regulates CD4/CD8 Differentiation Immunity. ,vol. 19, pp. 83- 94 ,(2003) , 10.1016/S1074-7613(03)00176-6
Beverley Wilkinson, Jeff Y.-F. Chen, Peggy Han, Kevin M. Rufner, Olivia D. Goularte, Jonathan Kaye, TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nature Immunology. ,vol. 3, pp. 272- 280 ,(2002) , 10.1038/NI767