Transition-metal-free tandem radical thiocyanooxygenation of olefinic amides: a new route to SCN-containing heterocycles.
作者： Hua Yang , Xin-Hua Duan , Jing-Feng Zhao , Li-Na Guo
DOI: 10.1021/ACS.ORGLETT.5B00754
关键词: Cascade reaction 、 Organic chemistry 、 Chemistry 、 One-Step 、 Transition metal 、 Potassium thiocyanate 、 Tandem 、 Combinatorial chemistry 、 Molecule
摘要: A novel transition-metal-free tandem radical thiocyanooxygenation of olefinic amides with potassium thiocyanate has been developed under mild conditions. This method allows a reliable and practical access to diverse SCN-containing heterocycles bearing wide range functional groups in good excellent yields. Furthermore, this reaction provides simple for the construction C-O C-S bonds one step.
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