Population-based surveillance for 2009 pandemic influenza A (H1N1) virus in Guatemala, 2009.

摘要: Please cite this paper as: Reyes et al. (2010) Population-based surveillance for 2009 pandemic influenza A (H1N1) virus in Guatemala, 2009. Influenza and Other Respiratory Viruses 4(3), 129–140. Background  In April 2009, H1N1 (2009 H1N1) was first identified Mexico but did not cause widespread transmission neighboring Guatemala until several weeks later. Methodology principle findings  Using a population-based system hospitalized pneumonia influenza-like illness ongoing before the began, we tracked onset of infection Guatemala. We 239 individuals infected with between May December whom 76 were 11 died (case fatality proportion: 4·6%, 95% confidence interval [CI] 2·3–8·1%). The median age patients 8·8 years, those 4·2 years, five (45·5%) deaths occurred children <5 years old. Crude rates hospitalization highest Twenty-one (27·6%) admitted to intensive care unit eight (10·5%) required mechanical ventilation. Underlying chronic conditions noted 14 (18·4%) infection. Conclusions significance  Chronic illnesses may be underdiagnosed making it difficult identify risk group vaccination. Children 6 months 5 years old should among priority groups vaccination prevent serious consequences because infection.