The glycophorin A assay for somatic cell mutations in humans.

作者: R.G. Langlois , W.L. Bigbee , R.H. Jensen

DOI:

关键词: GlycophorinBiologyAntibodyMutagenesis (molecular biology technique)Somatic cellMutation frequencyHaematopoiesisPopulationGeneticsCell culture

摘要: In this report we briefly review our past experience and some new developments with the GPA assay. Particular emphasis will be placed on two areas that affect utility of assay for human population monitoring. The first is efforts to simplify make it more generally available large studies. second begin understand characteristics hemopoiesis which accumulation expression mutant phenotype cells. 11 refs., 4 figs.

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