Spasticity Management in Disorders of Consciousness

摘要: Background: Spasticity is a motor disorder frequently encountered after lesion involving the central nervous system. It hypothesized to arise from an anarchic reorganization of pyramidal and parapyramidal fibers leads hypertonia hyperreflexia affected muscular groups. While this symptom its management well-known in patients suffering stroke, multiple sclerosis or spinal cord lesion, little known regarding appropriate presenting disorders consciousness brain damage. Objectives: Our aim was review occurrence spasticity with therapeutic interventions used treat it. Methods: We conducted systematic using PubMed online database. returned 157 articles. After applying our inclusion criteria (i.e., studies about coma, unresponsive wakefulness syndrome minimally conscious state, objectively reported as primary secondary outcome), 18 were fully reviewed. Results: The prevalence ranged 59% 89%. Current treatment options include intrathecal baclofen soft splints. Several still need further investigation; including acupuncture, botulin toxin cortical activation by thalamic stimulation. Conclusion: small number articles available current literature highlights that poorly studied although it one most common disorders. treatments such splints seem effective, large randomized controlled trials have be done new should explored.