Relationship between arterial blood pressure disturbances and alpha adrenoceptor density.
作者： M. Galinier , J. M. Senard , P. Valet , J. P. Doazan , G. Durrieu
DOI: 10.3109/10641969409072223
关键词: Alpha adrenoceptor 、 Plasma levels 、 Control subjects 、 Platelet 、 Central nervous system disease 、 Internal medicine 、 Orthostatic vital signs 、 Blood pressure 、 Medicine 、 Endocrinology 、 Catecholamine
摘要: To investigate the influence of blood pressure disturbances on human platelet alpha2-adrenoceptor density, we studied 7 normotensive Parkinsonians with orthostatic hypotension and 23 mild essential hypertensive patients. Plasma catecholamine levels were measured by HPLC number affinity determined [3H]-yohimbine binding. Alpha-adrenergic reactivity was investigated response to noradrenaline infusion in adrenaline-induced aggregation In hypotension, comparison without control subjects age sex matched, plasma significantly lower (62 ±11, 195 ±14 219 ±13 pg. ml−1 respectively, p < 0.05), alpha2—adrenoceptor
informahealthcare.com参考文章(17)
B Folkow, Physiological aspects of primary hypertension. Physiological Reviews. ,vol. 62, pp. 347- 504 ,(1982) , 10.1152/PHYSREV.1982.62.2.347
D S Goldstein, Plasma catecholamines and essential hypertension. An analytical review. Hypertension. ,vol. 5, pp. 86- 99 ,(1983) , 10.1161/01.HYP.5.1.86
K Sakaguchi, R Hattori, Y Yui, Y Takatsu, T Susawa, N Yui, H Nonogi, S Tamaki, C Kawai, Altered platelet alpha 2 adrenoreceptor in acute myocardial infarction and its relation to plasma catecholamine concentrations. Heart. ,vol. 55, pp. 434- 438 ,(1986) , 10.1136/HRT.55.5.434
ALAIN VILLENEUVE, MICHEL BERLAN, MAX LAFONTAN, CLAUDINE CARANOBE, BERNARD BONEU, ANDRÉ RASCOL, JEAN-LOUIS MONTASTRUC, Platelet alpha2 adrenoceptors in Parkinson's disease: decreased number in untreated patients and recovery after treatment European Journal of Clinical Investigation. ,vol. 15, pp. 403- 407 ,(1985) , 10.1111/J.1365-2362.1985.TB00292.X
P. Weidmann, M. Grimm, A. Meier, Z. Glück, G. Keusch, I. Minder, C. Beretta-Piccoli, Pathogenic and Therapeutic Significance of Cardiovascular Pressor Reactivity as Related to Plasma Catecholamines in Borderline and Established Essential Hypertension Clinical and Experimental Hypertension. ,vol. 2, pp. 427- 449 ,(1980) , 10.3109/10641968009037123
Otto-Erich Brodde, Anton E. Daul, Naoki OʼHara, Adel M. Khalifa, Properties of α- and β-adrenoceptors in Circulating Blood Cells of Patients with Essential Hypertension Journal of Cardiovascular Pharmacology. ,vol. 7, ,(1985) , 10.1097/00005344-198500076-00028
JM Senard, O Rascol, G Durrieu, MA Tran, M Berlan, A Rascol, JL Montastruc, None, Effects of yohimbine on plasma catecholamine levels in orthostatic hypotension related to Parkinson disease or multiple system atrophy. Clinical Neuropharmacology. ,vol. 16, pp. 70- 76 ,(1993) , 10.1097/00002826-199302000-00008
R Brian Haynes, Andrew C. Harper, Samuel R. Costley, Mary Johnston, Alexander G. Logan, Patrick T. Flanagan, David L. Sackett, Failure of weight reduction to reduce mildly elevated blood pressure: a randomized trial. Journal of Hypertension. ,vol. 2, pp. 535- 539 ,(1984) , 10.1097/00004872-198410000-00014
P Valet, C Damase‐Michel, B Chamontin, D Durand, F Chollet, JL Montastruc, None, Platelet α2- and leucocyte β2-adrenoceptors in phaeochromocytoma: effect of tumour removal European Journal of Clinical Investigation. ,vol. 18, pp. 481- 485 ,(1988) , 10.1111/J.1365-2362.1988.TB01043.X
V.G Thomas, Myoglobin levels and mATPase activity in pectoral muscles of spruce and ruffed grouse (Aves: Tetraoninae) Comparative Biochemistry and Physiology Part A: Physiology. ,vol. 81, pp. 181- 184 ,(1985) , 10.1016/0300-9629(85)90285-3