PEG Molecular Net-Cloth Grafted on Polymeric Substrates and Its Bio-Merits

摘要: Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for first time, we report a non-swelling “PEG molecular net-cloth” solid surface, fabricated using novel “visible light induced surface controlled graft cross-linking polymerization” (VSCGCP) technique. Via this method, show that 1) 3D-network structure of net-cloth be precisely modulated its thickness controlled; 2) PEG has excellent resistance non-specific protein adsorption cell adhesion; 3) mild polymerization conditions (i.e. visible room temperature) provided an ideal tool in situ encapsulation delicate biomolecules such as enzymes; 4) successive grafting reactive three-dimensional patterns enables creation microarrays with high signal noise ratio. Importantly, strategy is applicable any C-H containing easily tailored broad range applications.