Impact of obesity and body fat distribution on cardiovascular risk factors in Hong Kong Chinese.

作者: G. Neil Thomas , Sai-Yin Ho , Karen S.L. Lam , Edward D. Janus , Anthony J. Hedley

DOI: 10.1038/OBY.2004.224

关键词: Insulin resistanceObesityPopulationWaistInternal medicineBlood pressureInsulinOverweightPhysiologyMetabolic syndromeMedicineEndocrinology

摘要: Objective: Body fat distribution has been reported to differentially contribute the development of cardiovascular risk. We report relative associations between general and central obesity risk factors in 2893 Chinese subjects recruited from Hong Kong population. Research Methods Procedures: Anthropometric parameters [waist circumference (WC) BMI], surrogate measures insulin resistance (fasting plasma glucose insulin, oral tolerance test, 2 hours insulin), fasting lipids (total, low-density lipoprotein-cholesterol, high-density triglycerides) systolic diastolic blood pressure were measured. General was classified as BMI ≥25.0 kg/m2 a WC ≥80 or ≥90 cm women men, respectively. Results: A total 39.2% population found be obese. Obesity per se increased levels factors, but adiposity contributed greater extent adverse triglyceride, levels. There continuous relationship increasing obesity, both central, risk, with lowest associated indices obesity. In 1759 nonobese divided into quartiles WC, still significantly adiposity. Discussion: Central appears than this population. The is continuum, even at usually considered nonobese. These observations support proposed redefinition overweight Asian populations using lower cut-off points.

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