Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle.

作者: Bridget M Deasy , Joseph M Feduska , Thomas R Payne , Yong Li , Fabrisia Ambrosio

DOI: 10.1038/MT.2009.136

关键词: Vascular endothelial growth factorCancer researchSkeletal muscleMyocyteAngiogenesisMuscular dystrophyTransplantationMyogenesisImmunologyVascular endothelial growth factor ABiology

摘要: … Our findings suggest that VEGF-expressing MDSC increase both vascularization and endogenous muscle regeneration and decreased fibrosis after implantation in dystrophic skeletal …

参考文章(42)
Kenneth Urish, Yasunari Kanda, Johnny Huard, Initial failure in myoblast transplantation therapy has led the way toward the isolation of muscle stem cells: potential for tissue regeneration. Current Topics in Developmental Biology. ,vol. 68, pp. 263- 280 ,(2005) , 10.1016/S0070-2153(05)68009-X
S M Albelda, W A Muller, C A Buck, P J Newman, Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. Journal of Cell Biology. ,vol. 114, pp. 1059- 1068 ,(1991) , 10.1083/JCB.114.5.1059
Paul Gregorevic, Michael J Blankinship, James M Allen, Robert W Crawford, Leonard Meuse, Daniel G Miller, David W Russell, Jeffrey S Chamberlain, Systemic delivery of genes to striated muscles using adeno-associated viral vectors. Nature Medicine. ,vol. 10, pp. 828- 834 ,(2004) , 10.1038/NM1085
Arianna Dellavalle, Maurilio Sampaolesi, Rossana Tonlorenzi, Enrico Tagliafico, Benedetto Sacchetti, Laura Perani, Anna Innocenzi, Beatriz G. Galvez, Graziella Messina, Roberta Morosetti, Sheng Li, Marzia Belicchi, Giuseppe Peretti, Jeffrey S. Chamberlain, Woodring E. Wright, Yvan Torrente, Stefano Ferrari, Paolo Bianco, Giulio Cossu, Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nature Cell Biology. ,vol. 9, pp. 255- 267 ,(2007) , 10.1038/NCB1542
T. A. Partridge, J. E. Morgan, G. R. Coulton, E. P. Hoffman, L. M. Kunkel, Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts Nature. ,vol. 337, pp. 176- 179 ,(1989) , 10.1038/337176A0
Ron J Jankowski, Bridget M Deasy, Baohong Cao, Charley Gates, Johnny Huard, The role of CD34 expression and cellular fusion in the regeneration capacity of myogenic progenitor cells. Journal of Cell Science. ,vol. 115, pp. 4361- 4374 ,(2002) , 10.1242/JCS.00110
Paolo De Coppi, Dawn Delo, Lynn Farrugia, Kavid Udompanyanan, James J. Yoo, Masashi Nomi, Anthony Atala, Shay Soker, Angiogenic Gene-Modified Muscle Cells for Enhancement of Tissue Formation Tissue Engineering. ,vol. 11, pp. 1034- 1044 ,(2005) , 10.1089/TEN.2005.11.1034
George Karpati, Stirling Carpenter, Steven Prescott, Small‐caliber skeletal muscle fibers do not suffer necrosis in mdx mouse dystrophy Muscle & Nerve. ,vol. 11, pp. 795- 803 ,(1988) , 10.1002/MUS.880110802
T. Okano, K. Yoshida, A. Nakamura, F. Sasazawa, T. Oide, S. Takeda, S. Ikeda, Chronic exercise accelerates the degeneration-regeneration cycle and downregulates insulin-like growth factor-1 in muscle of mdx mice. Muscle & Nerve. ,vol. 32, pp. 191- 199 ,(2005) , 10.1002/MUS.20351
Hairong Peng, Arvydas Usas, Anne Olshanski, Andrew M Ho, Brian Gearhart, Gregory M Cooper, Johnny Huard, VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. Journal of Bone and Mineral Research. ,vol. 20, pp. 2017- 2027 ,(2005) , 10.1359/JBMR.050708