Assessing the feasibility of single lifetime PAP smear evaluation between 41-50 years of age as strategy for cervical cancer control in developing countries from our 32 years of experience of hospital-based routine cytological screening.

摘要: In view of the huge expenditure involved in mass cytological screening as well lack cytology manpower developing countries, single lifetime at 45 yr age has been suggested feasible strategy for control cervical cancer. The present study is aimed testing this hypothesis a broader prospective, accommodating women between 41 and 50 from data derived ongoing long-term hospital-based routine cervicovaginal Queen Mary's Hospital, Lucknow, India. smears 31,032 have evaluated cytologically during span 32 (April 1971-March 2003) early detection carcinoma cervix sexually transmitted diseases (STDs). incidence squamous intraepithelial lesions (SIL) was found to be 6.1% while frank malignancy seen 0.5% cases. following observations were made accumulated data: (a) approximately 30% total cancer cases group 41-50 yr; (b) maximum number SIL detected (35% cases), adequate management these would prevent occurring later years, thus minimizing 1.3% observed beyond age; (c) human papillomavirus (HPV) infection also quite high old, which onset/progression any premalignant changes cervix. Our experience substantiates an effective countries like ours.