MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice
作者： Shrikant R. Mulay , Dana Thomasova , Mi Ryu , Hans-Joachim Anders
DOI: 10.1038/KI.2011.482
关键词: Cytokine 、 Biology 、 Immunology 、 Inflammation 、 Proinflammatory cytokine 、 Mdm2 、 Cell cycle 、 Cell growth 、 Nutlin 、 Cancer research 、 Cell 、 Nephrology
摘要: … As such we assumed that therapeutic MDM2 inhibition will aggravate acute tubular necrosis and impair tubular regeneration in AKI, a theoretical concern that we addressed by studying …
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