p53-independent roles of MDM2 in NF-κB signaling: implications for cancer therapy, wound healing, and autoimmune diseases.
作者： Dana Thomasova , Shrikant R. Mulay , Hauke Bruns , Hans-Joachim Anders
DOI: 10.1593/NEO.121534
关键词:
摘要: … this review, we focus on the expanding role of MDM2 as a regulator of NF-κB signaling, innate immunity, and … Moreover, MDM2 can upregulate expression of p100/NF-κB2 in lung cells. …
core.ac.uk
sci-hub.se 参考文章(43)
Yinon Ben-Neriah, Michael Karin, Inflammation meets cancer, with NF-κB as the matchmaker Nature Immunology. ,vol. 12, pp. 715- 723 ,(2011) , 10.1038/NI.2060
Takashi Tokino, Takashi Tokino, Bert Vogelstein, Kenneth W. Kinzler, David Sidransky, David E. Hill, Jonathan D. Oliner, Sharon Smith, Marilee Burrell, Fredrick S. Leach, Paul Meltzer, p53 Mutation and MDM2 Amplification in Human Soft Tissue Sarcomas Cancer Research. ,vol. 53, pp. 2231- 2234 ,(1993)
Gang Liu, Young-Jun Park, Yuko Tsuruta, Emmanuel Lorne, Edward Abraham, p53 Attenuates Lipopolysaccharide-Induced NF-κB Activation and Acute Lung Injury Journal of Immunology. ,vol. 182, pp. 5063- 5071 ,(2009) , 10.4049/JIMMUNOL.0803526
Roberta Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano, Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 Nature. ,vol. 378, pp. 203- 206 ,(1995) , 10.1038/378203A0
Hilary V. Clegg, Koji Itahana, Yanping Zhang, Unlocking the Mdm2-p53 loop: ubiquitin is the key. Cell Cycle. ,vol. 7, pp. 287- 292 ,(2008) , 10.4161/CC.7.3.5358
Charles J. Sherr, Divorcing ARF and p53: an unsettled case Nature Reviews Cancer. ,vol. 6, pp. 663- 673 ,(2006) , 10.1038/NRC1954
Christine M. Eischen, Guillermina Lozano, p53 and MDM2: Antagonists or Partners in Crime? Cancer Cell. ,vol. 15, pp. 161- 162 ,(2009) , 10.1016/J.CCR.2009.02.004
Alla Polotskaia, Nandini Kundu, Jill Bargonetti, Angelika Brekman, Kathryn E Singh, A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation Breast Cancer Research. ,vol. 13, pp. 1- 14 ,(2011) , 10.1186/BCR2804
Shrikant R. Mulay, Dana Thomasova, Mi Ryu, Hans-Joachim Anders, MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice Kidney International. ,vol. 81, pp. 1199- 1211 ,(2012) , 10.1038/KI.2011.482
Lubing Gu, Ningxi Zhu, Harry W. Findley, William G. Woods, Muxiang Zhou, Identification and Characterization of the IKKα Promoter Journal of Biological Chemistry. ,vol. 279, pp. 52141- 52149 ,(2004) , 10.1074/JBC.M407915200