Subcutaneous mastectomy and immediate reconstruction for prevention of breast cancer for high-risk patients

摘要: Breast cancer is the most common malignant tumor among females in USA, with one out of eight American developing breast their lifetimes. The latest studies [1] show that 212,920 new cases invasive developed 2006, which 2.5 times more than incidence lung cancer, and 40,970 will die from this disease each year. Therefore, awareness an important health issue, women beginning to assess risk either informally or instruments such as GAIL model [2]. availability genetic testing for BRCA-1 BRCA-2 has revealed many who are at significantly increased risk. Many aggressive surveillance programs have been using advanced MRI ultrasound, reductions 50% proven chemoprevention strategies tamoxifen raloxifene. However, starting seriously consider prophylactic mastectomy near-total reduction At our institution, we a procedure subcutaneous via inframammary incision spares nipple combined immediate silicone implant reconstruction assistance Alloderm®. In article describe some issues surrounding its implementation experience.