作者: Kyung-Woo Lee , Hyun S. Lillehoj , Seung I. Jang , Guangxing Li , Sung-Hyen Lee
DOI: 10.1016/J.CIMID.2010.06.001
关键词: Biology 、 Broiler 、 Coccidiosis 、 Eimeria maxima 、 Weight gain 、 Splenocyte 、 Microbiology 、 Immunity 、 Bacillus subtilis 、 Immune system
摘要: The effect of dietary Bacillus-based direct-fed microbials (DFMs; eight single strains designated as Bs2084, LSSAO1, 3AP4, Bs18, 15AP4, 22CP1, Bs27, and Bs278, one multiple-strain DFM product [AVICORR]) on growth performance, intestinal lesions, innate acquired immunities were evaluated in broiler chickens following Eimeria maxima (EM) infection. EM-induced reduction body weight gain lesions significantly decreased by addition 15AP4 or Bs27 into diets compared with EM-infected control birds. Serum nitric oxide levels increased infected fed but lowered those given 3AP4 the controls. Recombinant coccidial antigen (3-1E)-stimulated spleen cell proliferation was Finally, all experimental concanavalin A-induced splenocyte mitogenesis broilers nonsupplemented In summary, Bacillus subtilis-based DFMs reduced clinical signs avian coccidiosis various parameters immunity a strain-dependent manner.