Topical Imiquimod in the Treatment of Conjunctival Actinic Keratosis.

作者: Megan A. Rowlands , Joseph N. Giacometti , Javier Servat , Miguel A. Materin , Flora Levin

DOI: 10.1097/IOP.0000000000000432

关键词: KeratosisTopical imiquimodMedicineCryotherapyBasal cellOcular irritationDermatologyConjunctivaActinic keratosisImiquimodSurgery

摘要: Conjunctival actinic keratosis is rare and difficult to treat, as recurrences are common. Imiquimod, an immune response modulator, currently Food Drug Administration-approved for cutaneous superficial basal cell carcinomas. Emerging reports have shown it be effective in treating some periocular conjunctival lesions. The authors present a case of 68-year-old white man with recurrent involving the pretarsal conjunctiva, which was successfully treated 5% topical imiquimod following previous failure cryotherapy interferon α-2b. patient had ocular irritation that resolved on cessation treatment. To authors' knowledge, this first report being eradicated by imiquimod.

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