Postnatal MRI Brain in Infants Treated for Twin-Twin Transfusion Syndrome.
作者： F Malone , S Ryan , A Lyons , A Poran , M Boyle
DOI:
关键词: Mri brain 、 Surgery 、 Gestational age 、 Prospective cohort study 、 Medicine 、 Fetoscopy 、 Magnetic resonance imaging 、 Case-control study 、 Pregnancy 、 Laser surgery
摘要: Untreated twin-twin transfusion syndrome (TTTS) is associated with significant mortality and neurological impairment. Fetoscopic laser surgery (FLS) the treatment of choice. We sought to assess intracranial abnormalities in TTTS twins following treatment. In this prospective, blinded study MRI scans were performed on 3 groups; (1) monochorionic diamniotic (MCDA) who had undergone FLS (n = 10), (2) MCDA without 8) (3) dichorionic 8). Scans scored as either normal or abnormal. The primary outcome was a composite abnormal brain intrauterine fetal demise. occurred 6/10 (60%) group versus 3/8 (37.5%) group. significantly different across all groups [p 0.029; X2 7.112]. found that treated for are more likely have at term than other twin groups. This merits term-corrected part their postnatal assessment.
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