No impact of DvSnf7 RNA on honey bee (Apis mellifera L.) adults and larvae in dietary feeding tests

摘要: The honey bee (Apis mellifera L.) is the most important managed pollinator species worldwide and plays a critical role in pollination of diverse range economically crops. This to agriculture historically has been used as surrogate for pollinators evaluate potential adverse effects conventional, biological, microbial pesticides, well genetically engineered plants that produce pesticidal products. As part ecological risk assessment MON 87411 maize, which expresses double-stranded RNA targeting Snf7 ortholog (DvSnf7) western corn rootworm (Diabrotica virgifera virgifera), dietary feeding studies with larvae adults were conducted. Based on mode action DvSnf7 rootworm, present designed be sufficient duration larval survival development through emergence adult significant portion stage. Testing was conducted at concentrations greatly exceeded environmentally relevant exposure levels based expression maize pollen. No observed either or bees these high levels, providing large margin safety between environmental no-observed–adverse-effect levels. Environ Toxicol Chem 2016;35:287–294. © 2015 Authors. Environmental Toxicology Chemistry Published by Wiley Periodicals, Inc. behalf SETAC.