A Fluorescence Switch for the Detection of Nitric Oxide and Histidine and Its Application in Live Cell Imaging
作者： Gandhi Sivaraman , Thangaraj Anand , Duraisamy Chellappa , None
关键词: Histidine 、 Fluorescence 、 Reactive nitrogen species 、 Copper 、 Reactive oxygen species 、 Live cell imaging 、 Photochemistry 、 Chemistry 、 Nitric oxide 、 Rhodamine
摘要: A rhodamine-based copper complex as a selective, sensitive turn-on fluorescent chemosensor for NO/histidine has been developed. conspicuous fluorescence enhancement was observed in the presence of nitric oxide/histidine. The probe specific towards NO over other reactive oxygen species and nitrogen species. showed selective with histidine; naturally occurring amino acids did not result enhancement. EPR ESIMS studies clearly that NO-induced reduction ions leads to viability imaging oxide histidine living cells demonstrated by means confocal laser scanning microscopy experiments.
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