On-Line Detection of Apnea/Hypopnea Events Using SpO $_{\bf 2}$ Signal: A Rule-Based Approach Employing Binary Classifier Models

作者: Bijoy Laxmi Koley , Debangshu Dey

DOI: 10.1109/JBHI.2013.2266279

关键词: Speech recognitionTime domainArtificial intelligencePattern recognitionBinary numberComputer scienceFeature extractionClassifier (UML)Binary classificationHypopneaSupport vector machineRule-based system

摘要: This paper presents an online method for automatic detection of apnea/hypopnea events, with the help oxygen saturation (SpO2) signal, measured at fingertip by Bluetooth nocturnal pulse oximeter. Event is performed identifying abnormal data segments from recorded SpO 2 employing a binary classifier model based on support vector machine (SVM). Thereafter segment further analyzed to detect different states within segment, i.e., steady, desaturation, and resaturation, another SVM-based ensemble model. Finally, heuristically obtained rule-based system used identify events time-sequenced decisions these models. In developmental phase, set 34 time domain-based features was extracted segmented SpO2 signal using overlapped windowing technique. Later, optimal selected basis recursive feature elimination A total subjects were included in study. The results show average event accuracies 96.7% 93.8% offline tests, respectively. proposed provides direct estimation index relatively inexpensive widely available Moreover, can be monitored accessed physicians through LAN/WAN/Internet extended deploy Bluetooth-enabled mobile phones.

参考文章(38)
Jean Louis Pépin, Patrick Lévy, Bruno Lepaulle, Christian Brambilla, Christian Guilleminault, Does Oximetry Contribute to the Detection of Apneic Events?: Mathematical Processing of the SaO2 Signal Chest. ,vol. 99, pp. 1151- 1157 ,(1991) , 10.1378/CHEST.99.5.1151
Ahsan H. Khandoker, Chandan K. Karmakar, Marimuthu Palaniswami, Automated recognition of patients with obstructive sleep apnoea using wavelet-based features of electrocardiogram recordings Computers in Biology and Medicine. ,vol. 39, pp. 88- 96 ,(2009) , 10.1016/J.COMPBIOMED.2008.11.003
Udantha R Abeyratne, Ajith S Wakwella, Craig Hukins, Pitch jump probability measures for the analysis of snoring sounds in apnea. Physiological Measurement. ,vol. 26, pp. 779- 798 ,(2005) , 10.1088/0967-3334/26/5/016
Juan-Carlos Vázquez, Willis H Tsai, W Ward Flemons, Akira Masuda, Rollin Brant, Eric Hajduk, William A Whitelaw, John E Remmers, Automated analysis of digital oximetry in the diagnosis of obstructive sleep apnoea Thorax. ,vol. 55, pp. 302- 307 ,(2000) , 10.1136/THORAX.55.4.302
Roberto Hornero, Daniel Alvarez, Daniel Abasolo, Flix del Campo, Carlos Zamarron, Utility of Approximate Entropy From Overnight Pulse Oximetry Data in the Diagnosis of the Obstructive Sleep Apnea Syndrome IEEE Transactions on Biomedical Engineering. ,vol. 54, pp. 107- 113 ,(2007) , 10.1109/TBME.2006.883821
J. Víctor Marcos, Roberto Hornero, Daniel Álvarez, Félix Del Campo, Mateo Aboy, Automated detection of obstructive sleep apnoea syndrome from oxygen saturation recordings using linear discriminant analysis. Medical & Biological Engineering & Computing. ,vol. 48, pp. 895- 902 ,(2010) , 10.1007/S11517-010-0646-6
D Álvarez, R Hornero, D Abásolo, F del Campo, C Zamarrón, Nonlinear characteristics of blood oxygen saturation from nocturnal oximetry for obstructive sleep apnoea detection. Physiological Measurement. ,vol. 27, pp. 399- 412 ,(2006) , 10.1088/0967-3334/27/4/006
J. Martin Bland, DouglasG. Altman, Statistical methods for assessing agreement between two methods of clinical measurement. The Lancet. ,vol. 327, pp. 307- 310 ,(1986) , 10.1016/S0140-6736(86)90837-8
Patrick Lévy, Jean Louis Pépin, C. Deschaux-Blanc, B. Paramelle, Christian Brambilla, Accuracy of Oximetry for Detection of Respiratory Disturbances in Sleep Apnea Syndrome Chest. ,vol. 109, pp. 395- 399 ,(1996) , 10.1378/CHEST.109.2.395
J. V. Marcos, R. Hornero, D. Álvarez, M. Aboy, F. Del Campo, Automated Prediction of the Apnea-Hypopnea Index from Nocturnal Oximetry Recordings IEEE Transactions on Biomedical Engineering. ,vol. 59, pp. 141- 149 ,(2012) , 10.1109/TBME.2011.2167971