作者: Nadia Gosselin , Annie Mathieu , Stéphanie Mazza , Anne Décary , Jacques Malo
DOI: 10.1016/J.NEULET.2006.08.046
关键词: P3a 、 Obstructive sleep apnea 、 Psychology 、 Sleep Stages 、 Apnea 、 Audiology 、 Vigilance (psychology) 、 Mismatch negativity 、 Cognition 、 Eye movement
摘要: Cognitive functions are altered in patients with obstructive sleep apnea syndrome (OSAS) and it has been proposed that vigilance attentional deficits play a pivotal role all aspects of these deficits. One way to assess system integrity is the study event-related-potentials (ERP), but only few ERP studies have conducted OSAS. The aim was use further impairments patients. Thirteen OSAS 13 age-matched controls underwent night polysomnographic recording. Each subject also tested an paradigm where standard (95%, 1000 Hz), high deviant (2.5%, 1250 Hz) low 1050 Hz) tones were presented. Subjects asked ignore stimuli read during task. Mismatch negativity (MMN) P3a amplitudes latencies measured. No between-group difference observed for stages, except lower percentage rapid eye movement (REM) (p < 0.01). Moreover, group showed higher micro-arousal index more transitions than control (p < 0.05). A significant effect found amplitude component (p < 0.05) both tones. MMN latencies. In conclusion, specific alterations reflects involuntary attention switching, automatic auditory processing assessed by appears be preserved.