Guidelines for cardiac monitoring of children during and after anthracycline therapy: report of the Cardiology Committee of the Childrens Cancer Study Group.

摘要: The anthracycline antibiotics, daunorubicin, doxorubicin, and the newer derivatives, are important components of many antineoplastic chemotherapeutic regimens. Their usefulness is limited by their cardiotoxicity. Sequential monitoring cardiac function patients undergoing chemotherapy allows identification subclinical In can thus guide modification to minimize cumulative cardiotoxicity, reducing acute long-term clinical sequelae. Such also aids in comparison cardiotoxicity produced different drugs methods schedules drug administration. considerable variability regimens between institutions literature has detracted from its usefulness. Cardiology Committee Childrens Cancer Study Group has, therefore, reviewed field formulated recommendations for standardized noninvasive children during immediately after where indicated.