作者: F. N. Marzulli , H. I. Maibach
DOI:
关键词: Sensitization 、 Contact sensitization 、 Skin sensitization 、 Drug 、 Medicine 、 Pharmacology 、 Antimicrobial 、 Dermatology
摘要: Synopsis Predictive CONTACT SKIN SENSITIZATION data have been developed for 23 ANTIMICROBIAL AGENTS using the DRAIZE procedure on normal human test subjects. In some cases results are exploratory and involve about 50 subjects; in most 100 or more subjects were used meaningful sensitization indices obtained. The antimicrobials currently use contemplated as cosmetic drug PRESERVATIVES their GERMICIDAL PROPERTIES when skin.