Stem Cell Therapy and Administration Routes After Stroke

摘要: Cell-based therapy has demonstrated safety and efficacy in experimental animal models of stroke, as well stroke patients. However, various questions remain regarding the therapeutic window, dosage, route administration, most appropriate cell type source, mechanisms action immune-modulation to optimize treatment based on stem therapy. Various delivery routes have been used models, including intracerebral, intraventricular, subarachnoid, intra-arterial, intraperitoneal, intravenous, intranasal routes. From a clinical point view, it is necessary demonstrate which feasible, safest, effective for use with Therefore, further studies concerning safety, efficacy, involved these effects are required determine their optimal use.