FLOW INJECTION CHEMILUMINESCENCE DETERMINATION OF ETHAMSYLATE BASED ON PERMANGANATE OXIDATION

作者: Jianxiu Du , Yinhuan Li , Ying Tang , Jiuru Lu

DOI: 10.1081/AL-120002680

关键词: ChemistryChemiluminescenceFormic acidPotassium permanganateEtamsylatePermanganateQuantitative analysis (chemistry)Analytical chemistryDetection limitEthamsylateChromatography

摘要: ABSTRACT A new flow injection chemiluminescence method is described for the determination of ethamsylate. The based on measurement signal produced from oxidation ethamsylate by potassium permanganate in acidic solution, enhanced formic acid. allows over range 1.0 × 10−8– 2.0 10−6 g ml−1 with a sample frequency 180 samples h−1. detection limit 5 10−9 g ml−1 and relative standard deviation 1.4% 5.0 10−7 g ml−1 solution eleven replicate measurements. was successfully applied to pharmaceutical preparations. brief discussion reaction mechanism has also given.

参考文章(19)
Isidro S. Monzó, Juan Palou, Joaquín Peñalver, Rosa Valero, Kinetics of the permanganate oxidation of formic acid in aqueous solution International Journal of Chemical Kinetics. ,vol. 19, pp. 741- 755 ,(1987) , 10.1002/KIN.550190807
X.R. Zhang, W.R.G. Baeyens, G.Van Der Weken, A.C. Calokerinos, K. Imai, Chemiluminescence determination of some local anaesthetics Analytica Chimica Acta. ,vol. 303, pp. 137- 142 ,(1995) , 10.1016/0003-2670(94)00517-P
Danuta. Slawinska, Janusz. Slawinski, Chemiluminescent flow method for determination of formaldehyde Analytical Chemistry. ,vol. 47, pp. 2101- 2109 ,(1975) , 10.1021/AC60363A040
Nikolaos T. Deftereos, Antony C. Calokerinos, Constantinos E. Efstathiou, Flow injection chemiluminometric determination of epinephrine, norepinephrine, dopamine and L-dopa Analyst. ,vol. 118, pp. 627- 632 ,(1993) , 10.1039/AN9931800627
Leonidas P Palilis, Antony C Calokerinos, Analytical applications of chemiluminogenic reactions Analytica Chimica Acta. ,vol. 413, pp. 175- 186 ,(2000) , 10.1016/S0003-2670(00)00798-4
Anthony R.J. Andrews, Alan Townshend, Chemiluminescence detection of the benzodiazepine loprazolam Analytica Chimica Acta. ,vol. 227, pp. 65- 71 ,(1989) , 10.1016/S0003-2670(00)82646-X