作者: Xuan Wang , Hong-Yang Zhao , Fang-Cheng Zhang , Yun Sun , Zhi-Yong Xiong
DOI: 10.3109/07357907.2014.958234
关键词: Glioblastoma 、 Dendritic cell 、 Immunotherapy 、 Comparative trial 、 Poor prognosis 、 Immunology 、 Oncology 、 Internal medicine 、 Clinical trial 、 Glioma 、 Medicine 、 Survival rate
摘要: Objective: Glioblastoma multiforme (GBM) has a poor prognosis. The purpose of this systematic review and meta-analysis was to analyze the outcomes clinical trials which compared immunotherapy with conventional therapy for treatment malignant gliomas. Methods: PubMed, Cochrane Google Scholar databases were searched relevant studies. 2-year survival rate used evaluate effectiveness immunotherapy. Results: Of 171 studies identified, six comparative included in review. Immunotherapy associated significantly longer OS therapy. Conclusion: may improve patients GBM.