Red blood cell distribution width and atrial fibrillation in patients with sick sinus syndrome

作者: Panagiotis Korantzopoulos , Konstantinos Kyrlas , Tong Liu , Guangping Li , John A. Goudevenos

DOI: 10.1016/J.JJCC.2015.07.013

关键词: Population studyCardiologyReceiver operating characteristicMedicineRed blood cell distribution widthAnisocytosisArea under the curveAtrial fibrillationInternal medicineSSS*Sick sinus syndrome

摘要: Abstract Background Sick sinus syndrome (SSS) is associated with atrial fibrillation (AF). Red blood cell distribution width (RDW) a marker of anisocytosis erythrocytes and related to inflammatory stress. Recently, RDW has been AF. The aim the present study was evaluate potential association AF history in patients SSS. Methods Consecutive symptomatic SSS undergoing dual-chamber pacemaker implantation were screened. Baseline clinical, laboratory, echocardiographic, electrocardiographic parameters recorded. Conventional indexes also assessed. Multivariate logistic regression analysis receiver operating characteristic (ROC) curve for performed. Results final population consisted 101 (47 men); median age: 77 [73–82] years. demographic clinical characteristics comparable between tachy-brady (AF history) (n = 32) other forms (n = 69). Left diameter increased [44 (39–48) mm vs. 39 (36–44) mm; p = 0.05]. Also, greater these [14.7 (13.6–15.4)% 13.7 (13.4–14.3)%; p = 0.02]. showed that independently (OR: 1.58; 95% CI: 1.06–2.85; p = 0.04). ROC area under 0.69 (p = 0.028). A cut-off point 14 sensitivity 70% specificity 69%. Conclusion prognostic value terms future development arrhythmia perpetuation should be further examined.

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