Genomic computing: explanatory modelling for functional genomics
作者： Douglas B. Kell , Jem J. Rowland , Richard J. Gilbert
DOI:
关键词: Computational biology 、 Bioinformatics 、 Gene 、 Biology 、 DNA microarray 、 Organism 、 Whole genome sequencing 、 Genomics 、 Minimal genome 、 Genetic programming 、 Functional genomics
摘要: Many newly discovered genes are of unknown function. DNA microarrays a method for determining the expression levels all in an organism which complete genome sequence is available. By comparing changes under different conditions it should be possible to assign functions these genes. However, many hundreds thousands data points may produced over series experiments. Genetic programming provided simple explanatory rules gene function from such datasets, where previous approaches had not succeeded.
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