Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase.
作者： S. Patra , S. Ghosh , S. Bera , A. Roy , S. Ray
DOI: 10.1134/S0006297909070037
关键词: Antiserum 、 Myeloid leukemia 、 Cell 、 Polyclonal antibodies 、 Sarcoma 、 Leukemia 、 Molecular biology 、 Ehrlich ascites carcinoma 、 Glyceraldehyde 3-phosphate dehydrogenase 、 Biology 、 Biochemistry
摘要: Here we describe the purification of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from normal leukocytes healthy subjects and chronic myeloid leukemia (CML) patients mouse muscle sarcoma tissue. The data indicate that some properties GAPDH CML tissues are similar also to those EAC (Ehrlich ascites carcinoma) cellular but distinctly different GAPDH. Polyclonal antiserum raised against 54 kDa subunit cell strongly reacted with tissue only weakly leukocyte a variety other rats. Both subunits were partially sequenced N-terminus compared known sequences altered three malignant sources might be common feature all cells, which is discussed in relation glycolysis aberrations.
springer.com
sci-hub.se 参考文章(44)
Manju Ray, Nandita Basu, Subhankar Ray, INACTIVATION OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE OF HUMAN MALIGNANT CELLS BY METHYLGLYOXAL Molecular and Cellular Biochemistry. ,vol. 177, pp. 21- 26 ,(1997) , 10.1023/A:1006831511527
Saroj P. Mathupala, Annette Rempel, Peter L. Pedersen, Aberrant glycolytic metabolism of cancer cells: A remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for Type II hexokinase Journal of Bioenergetics and Biomembranes. ,vol. 29, pp. 339- 343 ,(1997) , 10.1023/A:1022494613613
PV Dan'shina, EV Schmalhausen, D Yu Arutiunov, AP Pleten', VI Muronetz, Acceleration of glycolysis in the presence of the non-phosphorylating and the oxidized phosphorylating glyceraldehyde-3-phosphate dehydrogenases. Biochemistry. ,vol. 68, pp. 593- 600 ,(2003) , 10.1023/A:1023968028884
Om P. Malhotra, Prakash Prabhakar, Trishna Gupta, Arvind M. Kayastha, Phosphoglycerate-kinase-glyceraldehyde-3-phosphate-dehydrogenase interaction. Molecular mass studies. FEBS Journal. ,vol. 227, pp. 556- 562 ,(1995) , 10.1111/J.1432-1033.1995.TB20424.X
Swapna Ghosh, Kasturi Mukherjee, Manju Ray, Subhankar Ray, Identification of a critical lysine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cell. Comparison with the rabbit muscle enzyme. FEBS Journal. ,vol. 268, pp. 6037- 6044 ,(2001) , 10.1046/J.0014-2956.2001.02522.X
Svechnikova Ig, Ekström Tj, Lui Wo, Appelskog Ib, Almqvist Pm, Ammerpohl O, Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells International Journal of Oncology. ,vol. 24, pp. 1419- 1425 ,(2004) , 10.3892/IJO.24.6.1419
Michihiko Oguchi, Blanche P. Meriwether, Jane Harting Park, Interaction between Adenosine Triphosphate and Glyceraldehyde 3-Phosphate Dehydrogenase: III. MECHANISM OF ACTION AND METABOLIC CONTROL OF THE ENZYME UNDER SIMULATED IN VIVO CONDITIONS Journal of Biological Chemistry. ,vol. 248, pp. 5562- 5570 ,(1973) , 10.1016/S0021-9258(19)43541-2
E Christophers, U Mrowietz, J M Schröder, Purification and partial biologic characterization of a human lymphocyte-derived peptide with potent neutrophil-stimulating activity. Journal of Immunology. ,vol. 140, pp. 3534- 3540 ,(1988)
Swapna Bagui, Manju Ray, Subhankar Ray, Glyceraldehyde‐3‐phosphate dehydrogenase from Ehrlich ascites carcinoma cells FEBS Journal. ,vol. 262, pp. 386- 395 ,(1999) , 10.1046/J.1432-1327.1999.00384.X
Chisato Mori, Deborah A. O'brien, Paula L. Brown, Patricia L. Magyar, Edward M. Eddy, Jeffrey E. Welch, Jeffrey E. Welch, Donna O. Bunch, Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells. Journal of Andrology. ,vol. 21, pp. 328- 338 ,(2000) , 10.1002/J.1939-4640.2000.TB02111.X