Experimental Data on Chronic Magnesium Deficiency

摘要: Many studies have shown that magnesium ions play an important role in the regulation of cellular and physiological metabolism most systems within organism. Moreover, epidemiological indicate amounts consumed by considerable percentages population are below recommended intakes, hypomagnesemia is present 10% to 15% western population. However, clinical manifestations deficiency difficult define because depletion this cation associated with abnormalities many elements enzymes. If prolonged, insufficient intake may be responsible for symptoms attributed other causes, or whose causes unknown. experimental models laboratory animals been used investigate alterations caused deficiency, these can divided into two main types: acute lasting a few days, chronic which diet deficient given during period several weeks up 1 year. Chronic aim mimic situation observed countries, is, moderately low intakes o f sustained over long periods. In review we will summarize results reported from long-term animals.