Male Lineages in Brazil: Intercontinental Admixture and Stratification of the European Background

摘要: The non-recombining nature of the Y chromosome and well-established phylogeny Y-specific Single Nucleotide Polymorphisms (Y-SNPs) make them useful for defining haplogroups with high geographical specificity; therefore, they are more apt than Y-STRs to detect population stratification in admixed populations from diverse continental origins. Different Y-SNP typing strategies have been described address issues history movements within geographic territories interest. In this study, we investigated a set 41 Y-SNPs 1217 unrelated males five Brazilian geopolitical regions, aiming disclose genetic structure male lineages country. A comparison based on pairwise FST distances did not reveal statistically significant differences haplogroup frequency distributions among different regions. observed regions were, however, consistent colonization sample Northern region presented highest Native American ancestry (8.4%), whereas pronounced African contribution could be Northeastern (15.1%). Central-Western Southern samples showed higher European contributions (95.7% 93.6%, respectively). Southeastern (86.1%) (12.0%) contributions. subtyping most frequent lineage Brazil (R1b1a-M269) allowed background first time.