Context-dependent reorganization of spatial and movement representations by simultaneously recorded hippocampal and striatal neurons during performance of allocentric and egocentric tasks.

摘要: Hippocampal and striatal place- movement-correlated cell firing was recorded as rats performed place or response tasks in a familiar environment, then after cue manipulation. In field properties did not differ across brain structures task conditions. Movement correlates were stronger during performance only hippocampal neurons. After manipulations, movement-sensitive neurons changed their correlate strength, regardless of behavioral strategy. Thus, for both structures, place-correlated cells may encode spatial context information, whereas represent egocentric movement learned responses. The striking overall similarity between neural responses to manipulation (regardless strategy) suggests that these operate continuously, parallel, multiple forms learning.