作者: BK Kumar , VK Deekshit , P Rai , M Shekar , I Karunasagar
DOI: 10.1111/LAM.12210
关键词: Pathogen 、 Virulence 、 Gene 、 Hemolysin 、 Vibrio parahaemolyticus 、 Microbiology 、 Biology 、 Health risk 、 Pathogenicity
摘要: UNLABELLED Vibrio parahaemolyticus is a seafood-borne pathogen autochthonous to the marine and estuarine ecosystem, responsible for gastroenteritis when contaminated raw seafood consumed. The pathogenicity has been associated with thermostable direct haemolysin (TDH) TDH-related (TRH). Of late, presence of T3SS2α T3SS2β gene clusters well documented in clinical isolates known play an essential role pathogenesis. However, reports on T3SSβ genes V. isolated from and/or environmental samples are scanty. In this study, we have identified analysed distribution harvested along southwest coast India. Results showed that solely trh⁺ tdh⁺ /trh⁺ strains parahaemolyticus. Reverse transcriptase PCR (RT-PCR) were transcriptionally active. To our knowledge, study appears be first description T3SS2β-positive T3SS2 other virulence factors will help better understanding risk illness due SIGNIFICANCE AND IMPACT OF THE STUDY T3SSs (α or β) important contribute their humans. This demonstrated Mangalore coast. RT-PCR found functional. best such as TDH TRH highlights potential health consumers.