Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
作者： Feng Lan , Andrew S. Lee , Ping Liang , Veronica Sanchez-Freire , Patricia K. Nguyen
DOI: 10.1016/J.STEM.2012.10.010
关键词: Muscle hypertrophy 、 Missense mutation 、 Induced pluripotent stem cell 、 MYH7 、 Biology 、 Phenotype 、 Sudden cardiac death 、 Disease 、 Pathology 、 Homeostasis
摘要: Familial hypertrophic cardiomyopathy (HCM) is a prevalent hereditary cardiac disorder linked to arrhythmia and sudden cardiac death. While the causes of HCM have been identified as …
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