Resveratrol prevents CA1 neurons against ischemic injury by parallel modulation of both GSK-3β and CREB through PI3-K/Akt pathways.
作者： Fabrício Simão , Aline Matté , Aline S. Pagnussat , Carlos A. Netto , Christianne G. Salbego
DOI: 10.1111/J.1460-9568.2012.08229.X
关键词: Neuroprotection 、 CREB 、 Akt/PKB signaling pathway 、 Brain ischemia 、 Protein kinase B 、 Ischemia 、 Pharmacology 、 PI3K/AKT/mTOR pathway 、 Resveratrol 、 Biochemistry 、 Chemistry
摘要: … the CA1 hippocampus after ischemia/reperfusion. Furthermore… neuroprotective effect of resveratrol and decreased the level … ischemic rats pretreated with resveratrol increased Akt levels …
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