Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein

作者: Xiao Huan Liang , Linda K. Kleeman , Hui Hui Jiang , Gerald Gordon , James E. Goldman

DOI: 10.1128/JVI.72.11.8586-8596.1998

关键词: BiologySemliki Forest virusViral replicationViral loadSindbis virusApoptosisVirusProgrammed cell deathAlphavirusVirology

摘要: bcl-2, the prototypic cellular antiapoptotic gene, decreases Sindbis virus replication and Sindbis virus-induced apoptosis in mouse brains, resulting in protection against lethal …

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