Adverse Events Associated With Mohs Micrographic Surgery: Multicenter Prospective Cohort Study of 20 821 Cases at 23 Centers

摘要: Importance Detailed information regarding perioperative risk and adverse events associated with Mohs micrographic surgery (MMS) can guide clinical management. Much of the data complications MMS are anecdotal or report findings from single centers events. Objectives To quantify detect differences relevant to safety. Design, Setting, Participants Multicenter prospective inception cohort study 21 private 2 institutional US ambulatory referral for MMS. were a consecutive sample patients presenting 35 weeks at each center, staggered start times. Exposure surgery. Main Outcomes Measures Intraoperative postoperative minor serious Results Among 20 821 procedures, 149 (0.72%), including 4 (0.02%), no deaths reported. Common reported infections (61.1%), dehiscence partial full necrosis (20.1%), bleeding hematoma (15.4%). Most wound-healing occurred in receiving anticoagulation therapy. Use some antiseptics antibiotics sterile gloves during modest reduction Conclusions Relevance is safe, very low rate events, an exceedingly undetectable mortality rate. include infections, followed by impaired wound healing bleeding. Bleeding issues often preexisting therapy, which nonetheless managed safely We not certain whether small effects seen use clinically significant wide-scale practice changes would be cost-effective given reductions.