Pathology of AIDS-Study from a Neuropsychiatric Centre from South India

摘要: The pathomorphological features noted in 47 cases of HIV/AIDS studied on autopsy (39 cases) and surgical biopsy material (8 over a period 8.5 years are described here. serum samples all 26/29 CSF tested were positive for anti HIV antibodies. Majority patients young adult males the age group 25-35 years. History high risk behaviour was available 59.6% cases. 38/39 autopsied succumbed to various opportunistic infections. Infection by single pathogen 76.3% due multiple infectious agents 23.7%. commonest infection cryptococcosis (59%) followed toxoplasma encephalities (28.2%) tuberculous meningitis (25.6%). others included meningococcal meningitis, herpes simplex, cytomegalovirus acanthamoeba encephalitis one case each. Features leucoencephalitis tow brain specimens. Complete body necropsy carried out 11/39 revealed disseminated 5, tuberculosis 4 related changes lymphoreticular organs 3 Pneumocystis carinil pneumonia 2 along with cryptococcosis. Diagnostic lymph node lymphadenitis non-tuberculous mycobacteria one. Evidence IIIV associated neuropathy In present series, incidence cryptococcal very compared neurotuberculosis as reported from other clinical series parts India. Similarly, also higher. type laboratory support experience pathologist play crucial role accurate identification pathogens. Therefore, index suspicion proper diagnostic approach is required developing countries identify pathological lesions.