The spectrum of peripheral neuropathy in myeloma

作者: John J Kelly Jr , MD , Robert A Kyle , John M Miles , Peter C O'Brien

DOI: 10.1212/WNL.31.1.24

关键词: Endocrine systemHomogeneousMultiple myelomaPeripheral neuropathyChemotherapyPathologyMedicineMotor neuropathyRadiation therapy

摘要: The records of 20 patients with typical or sclerotic (sclerotic mixed and lytic) multiple myeloma peripheral neuropathy who were seen during a 13-year period analyzed to determine the natural history neuropathy. In 10 myeloma, clinical pattern was heterogeneous. Chemotherapy for did not affect had presented in relatively homogeneous manner, predominantly motor Tumoricidal radiation therapy localized plasmacytomas resulted pronounced improvement two patients, mild three, endocrine abnormalities one patient.

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