Method for producing the anticholinergic agent tiotropium bromide
作者： Peter Specht , Helmut Meissner , Andreas Mathes , Wolfgang Broeder , Sven Luettke
DOI:
关键词: Anticholinergic 、 Chemistry 、 Nonane 、 Tiotropium bromide 、 Organic chemistry 、 Bromide
摘要: The invention relates to a novel method for producing (1α, 2β, 4β, 5α, 7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4-] nonane bromide.
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Rudolf Dr. Bauer, Rolf Dr. Banholzer, Richard Dr. Reichl, Thienylcarboxylic acid ester of aminoalcohols, their quaternary products, their preparation and use of the compounds ,(1990)