Should we consider integrated approach for endometriosis-associated infertility as gold standard management? Rationale and results from a large cohort analysis

摘要: To evaluate reproductive and maternal–fetal outcomes after integrated approach for endometriosis-associated infertility (EAI). We retrospectively analyzed of 277 women affected by EAI, subdividing patients in two groups: the first one (surgery group), we included all who underwent laparoscopic surgery EAI; second (integrated failed to conceive spontaneously within 6–12 months vitro fertilization embryo transfer (IVF). evaluated delivery rate (DR), maternal neonatal pregnancies, and, finally, type (spontaneous or IVF) subsequent pregnancies. did not find significant difference regarding DR between groups. found significantly lower birth weight (p < 0.001) gestational age at group respect group; conversely, higher preterm (p < 0.001), small (p = 0.003), admission intensive care unit group. Finally, 92 became pregnant time: 8% were spontaneous 20% IVF suggest as gold standard treatment carefully selected (young, good ovarian reserve, partner with normal semen parameters) EAI. As consequence, should be reserved secondary fail 6–12 months, since it is able increase significantly.