Sex differences in the incidence and severity of respiratory tract infections

作者: Matthew E. Falagas , Eleni G. Mourtzoukou , Konstantinos Z. Vardakas

DOI: 10.1016/J.RMED.2007.04.011

关键词: OtitisRespiratory tract infectionsRespiratory diseaseIncidence (epidemiology)EpidemiologyInternal medicineImmunologyTonsillitisSinusitisBronchitisMedicine

摘要: Sex is a significant epidemiological factor for several diseases. However, the role of sex in development and outcome various infections has not been extensively studied with notable exception urinary tract infections. We searched PubMed database to identify articles that could provide relevant data regarding differences incidence severity respiratory (RTIs). extracted from 84 studies provided information RTIs. Females are more commonly affected upper tract, specifically sinusitis, tonsillitis, otitis externa. On other hand, males media, croup, most important, lower It also evident reviewed evidence course RTIs severe than females, leading higher mortality males, especially community-acquired pneumonia. In conclusion, available suggest susceptible females types all age groups (adults children). Overall, it seems develop frequently except externa, probably tonsillitis. Anatomic, lifestyle, behavioural, socioeconomic between may explain observed findings. The hormones regulation immune system contribute reported RTIs, adolescents adults.

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